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Updated: Feb 11, 2026

Generation of Subcutaneous and Intrahepatic Human Hepatocellular Carcinoma Xenografts in Immunodeficient Mice
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对犬肝细胞癌的分子洞察:与人类HCC进行跨物种转录基因比较

Mohammad Arif1,2, Md Nazmul Hasan1, Nobuhiro Nozaki1

  • 1Joint Graduate School of Veterinary Medicine, Kagoshima University, Kagoshima, Japan.

Molecular carcinogenesis
|February 10, 2026
PubMed
概括

这项研究揭示了狗和人类肝癌 (HCC) 之间的显著分子相似性,确定了共享的基因表达模式和途径. 这些发现表明,犬类HCC可以作为人类疾病研究和治疗开发的有价值的比较模型.

关键词:
生物信息学是一种生物信息学.生物标志物发现发现进行比较的基因组学.比较瘤学的比较.跨物种转录组学 跨物种转录组学肝细胞癌是肝细胞癌.下一代测序 (NGS) 是指下一代的测序.瘤性途径的发生.转录组的概况分析

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