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Updated: Feb 11, 2026

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大脑脊髓液中的N缩短的超氧化物脱酶-1被折叠并活跃

Laura Leykam1, Karin M E Forsberg2, Peter M Andersen2

  • 1Department of Medical Biosciences, Clinical Chemistry, Umeå University, Umeå, Sweden.

Journal of neurochemistry
|February 10, 2026
PubMed
概括

在大脑脊髓液中超氧化物脱酶-1 (SOD1) 的N端切断不会导致错误折叠或活动丧失. 这种截断的SOD1变体存在于与原生SOD1的异构体中,但其在肌缩侧面硬化症 (ALS) 中的作用仍然未知.

关键词:
骨髓缩侧面硬化症 (ALS) 是一种大脑脊髓液中的脑脊液.后翻译修改后的修改.超氧化物脱酶-1-1 的作用.

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