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Updated: Jun 21, 2026

Stereotaxic Infusion of Oligomeric Amyloid-beta into the Mouse Hippocampus
08:16

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Published on: June 17, 2015

粉样β刺激心脏神经损伤信号损伤,驱动与阿尔茨海默氏症相关的心脏病

Andrea Elia1, Rebecca Parodi-Rullan1,2, Rafael Vazquez-Torres1

  • 1Alzheimer's Center at Temple (ACT), Department of Neural Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|February 10, 2026
PubMed
概括

阿尔茨海默氏病 (AD) 病理,包括粉样β (Aβ) 沉积,通过破坏神经营养信号传递和引起心脏缩,直接损害心脏功能. 这项研究揭示了AD和心脏退化之间存在新的联系.

关键词:
阿尔茨海默氏症的疾病是阿尔茨海默氏症.大脑-心轴神经信号通路的神经信号通路心脏功能障碍的心脏功能障碍人类iPSC衍生的心肌细胞.人类死后心脏的心脏

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