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Updated: Feb 11, 2026

Synthesis of Keratin-based Nanofiber for Biomedical Engineering
14:43

Synthesis of Keratin-based Nanofiber for Biomedical Engineering

Published on: February 7, 2016

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在KshA的结构指导工程中,产生了一种高性能的9α-基酶,用于合成9α-OH-AD

Yanmei Dai1,2, Dongchang Sun2, Qingyu Zhang1

  • 1College of Pharmaceutical Science, Zhejiang Key Laboratory of Green Manufacturing Technology for Chemical Drugs, Zhejiang University of Technology, Hangzhou 310014, China.

ACS synthetic biology
|February 10, 2026
PubMed
概括

这项研究设计了一种优质的9α-基酶 (KSH) 酶变体,用于产生9α-基-4-氨基-3,17- (9α-OH-AD). 改进的酶显示出明显更高的活性,使工业类固醇制药中间体生产更有效.

关键词:
9α-基-4-氨酸-3,17-氨酸9α-基酶的存在指导进化是指导进化的.料批量转换的料批量转换.分子动力学模拟模拟半理性的设计.

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