南非的艾滋病毒自我测试和临床医生管理的测试:对程序性结果的系统审查
David W Flynn1, Cassandra Fairhead2, Katie Heath3
1School of Public Health, Imperial College London, UK.
AIDS (London, England)
|February 10, 2026
概括
与临床医生进行的检测相比,南非的艾滋病毒自我检测 (HIVST) 显示了高吸收率,但积极性和与护理的联系较低. 进一步的研究应侧重于改善HIVST计划与护理管理的联系.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 全球健康 全球健康
背景情况:
- 据估计,在2024年,全球约有530万艾滋病毒感染者 (PLHIV) 没有意识到自己的身份,南非面临着最大的负担.
- 了解艾滋病毒检测行为和结果对于高发病率地区有效的艾滋病毒预防和治疗策略至关重要.
研究的目的:
- 综合艾滋病毒检测吸收率,阳性率和与护理联系的程序证据.
- 为了比较临床医生管理的测试和南非艾滋病毒自我测试 (HIVST) 模式之间的结果.
主要方法:
- 系统审查计划层面的结果分析.
- 搜索包括2020-2025年间发表的来自南非国家的研究.
- 聚合几率比率和二项式通用线性模型被用于分析测试吸收率,阳性度和与护理的联系.
主要成果:
- 包括43项研究,涉及8个南非国家的290,428名参与者.
- 与临床医生管理的测试相比,HIVST项目显示了更高的测试吸收率 (OR=1.34),但较低的HIV阳性产量 (aOR=0.63).
- 在HIVST项目中,积极结果后与护理的联系明显较低 (OR=0.036).
结论:
- 南非的HIVST与高测试率相关,但阳性率降低和与护理的联系.
- 生态比较和结果测量异质性极限解释.
- 未来的研究必须优先考虑与HIVST计划的护理管理策略的强有力的联系.
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