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Updated: Feb 11, 2026

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ASO实践指南系列:膀癌复发的手术管理
Can Aydogdu1, Sean T McSweeney1, Vignesh T Packiam2
1Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.
Annals of surgical oncology
|February 10, 2026
概括
经过菌卡尔梅特-盖林 (BCG) 或三种疗法 (TMT) 治疗,治疗复发性膀癌需要平衡治疗与生活质量. 早期的激进囊切除术通常是建议的,对于精选的患者,可以选择节省膀的选择.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 癌症研究 癌症研究
背景情况:
- 在初始治疗 (如菌卡尔梅特-盖林 (BCG) 或三种疗法 (TMT) 之后,膀癌的复发会带来复杂的治疗挑战.
- 患有高风险非肌肉侵入性或肌肉侵入性膀癌的患者需要及时做出决定,以平衡瘤结果与生活质量.
研究的目的:
- 将当前的指导方针和关键试验数据转化为管理膀癌复发的实际决策策略.
- 为临床医生和患者提供一个明确的框架,在BCG或TMT失败后导航治疗选择.
主要方法:
- 审查主要泌尿和瘤学会 (AUA/SUO,NCCN,EAU) 的2024-2025年指南.
- 结合了关键临床试验和美国食品和药物管理局 (FDA) 最近批准的药物进展的数据.
- 强调临床决策和患者咨询的实际应用.
主要成果:
- 对于BCG后复发,急性囊切除术 (RC) 是医疗适合患者治愈的主要建议;严格监测的膀节约疗法是替代方案.
- 在TMT之后,RC是侵入性复发的标准,而膀保存则被考虑为选择的非侵入性病例.
- 在这两种情况下,最优的管理需要迅速评估,全面提出选择,以及多学科的投入,并进行密切的跟进.
结论:
- 膀癌复发的有效管理取决于将治疗与患者的目标相协调,并保护瘤结果.
- 多学科团队的早期参与和共享决策对于优化患者护理和结果至关重要.
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