通过单独的切口剖析腹淋巴结并不会增加与乳腺癌相关的淋巴的发生率
Jennifer Wang1, Jenny Chen1, Thomas Amburn2
1Plastic and Reconstructive Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Annals of surgical oncology
|February 10, 2026
概括
与乳腺切除切口相比,通过单独的切口进行状淋巴结解剖 (ALND) 并不会增加与乳腺癌相关的淋巴风险 (BCRL). 在选择外科手术技术时,瘤安全仍然至关重要.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 淋巴 edem 研究 研究 淋巴 edem 研究
背景情况:
- 骨淋巴结解剖 (ALND) 是一种标准的乳腺癌治疗方法,具有20-30%的淋巴的终身风险.
- 对ALND的手术方法 (乳腺切除与分开切口) 可能会影响淋巴干扰和随后的淋巴的发生率,尽管这一点尚不清楚.
研究的目的:
- 为了调查下淋巴结解剖 (ALND) 的切口部位是否会影响与乳腺癌相关的淋巴水 (BCRL) 的发生率.
主要方法:
- 在2017年至2020年期间,对1,036名接受乳腺切除和ALND的患者进行了回顾性图表审查.
- 患者根据ALND方法进行了分层:通过乳腺切除切口或单独的腹切口.
- 乳腺癌相关淋巴 (BCRL) 的发展,通过ICD-10代码识别,是主要的结果指标.
主要成果:
- 在两种ALND方法之间没有观察到BCRL率的显著差异 (29%的单独切口与30%的乳腺切口,p=0.77).
- 多变量分析表明,通过单独的切口进行ALND并没有显著增加患淋巴的几率 (OR 0.89;95% CI 0.65-1.21;p=0.45).
- 在两组中,淋巴瘤诊断的中位时间为15个月.
结论:
- 通过单独的关切口进行关淋巴结解剖 (ALND) 并不会导致与乳腺切口相比,与乳腺癌相关的淋巴水 (BCRL) 的发生率显著增加.
- 优先考虑瘤安全应该指导乳腺癌手术中选择淋巴结检索技术.
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