患者使用Guselkumab的满意度 自治使用单压装置治疗中度至严重的牛皮:来自葡萄牙国家,前性,现实世界的研究 (CERES研究) 的结果
Tiago Torres1, João Teles Sousa2, Joana Antunes3
1Unidade Local de Saúde de Santo António-Hospital Santo António, EPE, 4050-366, Porto, Portugal. torres.tiago@outlook.com.
Dermatology and therapy
|February 10, 2026
概括
在葡萄牙,通过One-Press设备自行给药Guselkumab显著改善了中度至重度斑块牛皮患者的患者满意度和生活质量. 该疗法在52周内显示出高临床有效性和良好的安全性.
科学领域:
- 皮肤病学 皮肤病学
- 免疫学 免疫学 免疫学
- 药理学 药理学是指药理学的学科.
背景情况:
- 一种IL-23抑制剂Guselkumab对斑块性牛皮有效.
- 关于葡萄牙患者对guselkumab One-Press设备的满意度的现实数据有限.
研究的目的:
- 通过使用One-Press设备评估患者对guselkumab自我管理的满意度.
- 在52周内评估生活质量,临床有效性和安全性.
主要方法:
- 对101名中度至重度斑块性牛皮的成年人进行了前性,多中心,全国性的研究.
- 在基线和第20周通过自我注射评估问卷 (SIAQ) 评估患者满意度.
- 生命质量 (DLQI),临床有效性 (IGA) 和安全性评估到第52周.
主要成果:
- 在SIAQ得分的显著改善 (在第20周的平均增加从6.9到8.3) 和减少注射焦虑.
- 在DLQI得分的显著改善,70.8%在第52周达到DLQI0/1
- 高临床有效性 (IGA 0/1在91.0%在52周) 和有利的安全性,主要是轻微的注射部位反应.
结论:
- 在葡萄牙的临床实践中,Guselkumab与One-Press设备的自给药是耐受良好且有效的.
- 一个压力设备提高了患者的满意度和斑块牛皮患者的生活质量.
- 现实世界的数据支持自给药的guselkumab的可用性和益处风险概况.
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