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自闭症和脑儿童的成长和神经心理发育相关性 - 一项试点研究
Rouzha Pancheva1, Melisa Ilhan2, Rositsa Chamova1
1Department of Hygiene and Epidemiology, Faculty of Public Health, Medical University "Prof. Dr Paraskev Stoyanov"- Varna, Bulgaria - Research Group NutriLect, Department of Neuroscience, Research Institute, Medical University "Prof. Dr. Paraskev Stoyanov"- Varna, Bulgaria.
患有脑 (CP) 的儿童比患有自闭症谱系障碍 (ASD) 的儿童更容易经历生长和发育迟缓. 体重与年龄的关系是神经发育结果的重要预测因素,特别是适应性行为.
科学领域:
- 神经科学是一个神经科学.
- 发育儿科 发育儿科
- 营养科学 营养科学
背景情况:
- 大脑 (CP) 和自闭症谱系障碍 (ASD) 是影响生长和神经心理发展的神经发育状况.
- 关于CP和ASD儿童身体生长指标和发育特征之间的关系的研究有限.
- 本研究比较了这些人群的发育特征,并研究了这些人群的成长与发展的联系.
研究的目的:
- 调查CP和ASD儿童的身体成长指标和神经心理发展之间的关系.
- 为了比较被诊断患有CP的儿童的发育概况与ASD.
- 确定预测神经发育结果的关键增长指标.
主要方法:
- 一项试点横截面研究涉及27名儿童 (14名患有CP,13名患有自闭症).
- 人类测量评估包括身高按年龄 (HAZ),体重按年龄 (WAZ),BMI按年龄 (BMIAZ),中上臂周长按年龄 (MUACAZ) 和皮厚度Z分数 (TSFAZ,SSFAZ).
- 通过使用多个领域的发育概况3 (DP-3) 评估神经心理发展.
主要成果:
- 与CP儿童相比,患有ASD的儿童在身体发育,适应性行为和整体发育方面的得分明显更高.
- 体重与年龄 (WAZ) 与适应性行为和整体发育有显著的相关性.
- WAZ成为神经发育得分的重要预测因子,解释了46.5%的差异.
结论:
- 与ASD儿童相比,患有CP的儿童表现出更明显的生长和发育迟缓.
- 体重与年龄是影响神经发育的关键因素,特别是适应性行为.
- 研究结果强调了将营养支持纳入神经发育障碍的发育护理策略的重要性.
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