佩戴手术口罩或N95口罩对患有稳定慢性超呼吸系统衰竭的患者的影响
Hayden Venville1, Mark R Elkins2, Olivia A McGuiness1
1Mr. Venville, Ms. McGuiness, and Drs. Piper and Menadue are affiliated with the Respiratory Support Service, Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Sydney, Australia.
Respiratory care
|February 10, 2026
概括
使用外科或N95口罩在使用非侵入性通风 (NIV) 的慢性高头症患者中没有显著改变气体交换. 然而,口罩确实增加了报告的呼吸障碍和呼吸不适.
科学领域:
- 呼吸系统医学 呼吸系统医学
- 肺部生理学 肺部生理学
- 医疗器械安全 医疗器械安全
背景情况:
- 手术和N95口罩对于预防呼吸道病毒传播至关重要.
- 面具的安全性已在健康个体中得到证实,但在患有慢性高头症的人中并未得到充分理解.
- 患有慢性高头症的患者往往不能耐受口罩.
研究的目的:
- 评估手术口罩和N95口罩对患有稳定慢性高头症的患者的生理影响.
- 评估口罩使用对气体交换和呼吸系统症状的影响.
- 为了确定口罩与非侵入性通风 (NIV) 结合使用的安全性和耐受性.
主要方法:
- 采用了一种随机交叉试验设计.
- 使用NIV评估了患有慢性头皮增大症的参与者.
- 测量包括氧和 (SpO2),通过皮肤排放的二氧化碳 (PtcCO2),心率,呼吸频率和呼吸障碍 (MDP和mBORG) 在休息时和没有面具时的尺度.
主要成果:
- 与没有面具相比,手术或N95口罩都没有显著影响SpO2或PtcCO2水平.
- 戴口罩的使用没有改变心率或呼吸频率.
- 这两种口罩类型都导致报告呼吸障碍的显著增加 (mBORG和MDP得分).
- 三名参与者因不适而过早停止使用口罩.
结论:
- 手术和N95口罩在NIV.慢性高头症患者中不会显著损害气体交换.
- 在这个患者群体中,口罩使用与主观呼吸不良和呼吸不适的增加有关.
- 可能需要进一步的研究来改善慢性呼吸道疾病患者的口罩耐受性.
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