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在PIP2和Ca2+结合位点门TMEM16A通道之间的合合

Jie Xu1,2,3, Ana Santa-Cruz1,2, Aishwarya Chandrashekar1,2

  • 1Department of Pharmaceutical Sciences, Center for Drug Discovery, School of Pharmacy and Pharmaceutical Sciences, Bouve College of Health Science, Northeastern University, Boston, MA 02115.

Proceedings of the National Academy of Sciences of the United States of America
|February 10, 2026
PubMed
概括

固醇4,5-双酸盐 (PIP2) 和 (Ca2+) 协同进入TMEM16A通道. 与Ca2+一起,PIP2头组和乙基链对于TMEM16A通道的激活和功能至关重要.

关键词:
在PIP2中,PIP2是PIP2.在TEMEM16A中使用.离子透通过透.分子动力学分子动力学

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