护理地点尿液诺福维尔药物水平反咨询改善了美国MSM在试点RCT中长期PrEP的坚持
Matthew A Spinelli1, Leah Davis Ewart2, Emily J Ross2
1University of California, San Francisco, California, U.S.
概括
一项新的远程干预措施改善了年轻男性对暴露前预防 (PrEP) 药物的坚持. 这种方法,使用尿液测试和动机面试,显示出高可行性和可接受性.
科学领域:
- 公共卫生 公共卫生
- 预防艾滋病毒 预防艾滋病毒
- 行为科学 行为科学
背景情况:
- 暴露前预防 (PrEP) 在预防艾滋病毒方面是有效的,但遵守可能具有挑战性,特别是在与男性发生性关系 (MSM) 的年轻男性中.
- 远程干预提供了一种可扩展的方法,以支持不同人群的药物坚持.
- 激励面试是一种以患者为中心的咨询风格,有效地改变行为.
研究的目的:
- 为了评估一个远程的有效性,动机采访信息化的干预使用自我管理的点的护理尿液tenofovir测试.
- 评估干预措施对美国与男性发生性关系的年轻男性 (MSM) 的暴露前预防 (PrEP) 坚持的影响.
主要方法:
- 一项试点随机试验与年轻的美国MSM进行.
- 参与者接受了远程干预,包括激励性采访和自我注射尿液诺福维尔测试.
- 使用头发诺福维尔水平来评估依从性.
主要成果:
- 这项干预措施显著改善了 PrEP 的长期坚持.
- 参与者每周增加一到两片药物的坚持.
- 这项干预表明了参与者的高可行性和可接受性.
结论:
- 远程,动机面试 - - 采用点照顾尿液检测的信息干预是一种有前途的策略,可以提高PrEP的坚持.
- 这种干预对于年轻的美国MSM来说是可行的和可以接受的.
- 该干预措施的进一步实施得到了试点试验结果的支持.
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