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Updated: Feb 12, 2026

Modeling Spontaneous Metastatic Renal Cell Carcinoma mRCC in Mice Following Nephrectomy
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探索FGF/FGFR通路与清细胞脏细胞癌中的瘤微环境之间的交叉

Takafumi Narisawa1, Sei Naito1, Yoshihide Mitsuda2

  • 1Department of Urology, Faculty of Medicine, Yamagata University, Yamagata, Japan.

PloS one
|February 10, 2026
PubMed
概括

纤维细胞生长因子受体1 (FGFR1) 在清细胞细胞癌 (ccRCC) 中升高,并通过招募瘤相关巨细胞 (TAM) 与免疫抑制性瘤微环境联系在一起. FGFR1可能是ccRCC的治疗生物标志物.

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