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用算法方法确定Mycobacterium结核病治疗的最佳组合方案:未来的预测和验证

Arnold Louie1, Michael Neely2, Sarah Kim1,3

  • 1Institute for Therapeutic Innovation, University of Florida College of Medicine Orlando, Florida, United States of America.

PloS one
|February 10, 2026
PubMed
概括

结合诸如普雷托曼尼德 (pretomanid),莫西弗洛克萨辛 (moxifloxacin) 和贝达奎林 (bedaquiline) 等药物的新途径有效治疗结核病. 这种组合疗法抑制了耐药性,并在动物模型中实现了细菌灭菌,为更短的结核病治疗提供了有希望的方法.

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