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Updated: Feb 12, 2026

Analysis of Liver Microenvironment During Early Progression of Non-Alcoholic Fatty Liver Disease-Associated Hepatocellular Carcinoma in Zebrafish
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布普勒鲁姆素通过调节Sirtuin 6来改善与代谢相关的脂肪肝疾病

Siqi Liu1, Penglong Chen2, Yayi Li1

  • 1State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510405, PR China.

Phytomedicine : international journal of phytotherapy and phytopharmacology
|February 10, 2026
PubMed
概括

布普勒鲁姆素 (Bc) 通过其成分赛可萨素C (SSc) 激活Sirtuin 6 (SIRT6) 以对抗与代谢相关的脂肪肝疾病 (MAFLD). 这种Bc-SSc-SIRT6通路改善脂质代谢和氧化应激,提供了一个新的治疗点.

关键词:
布普勒乌鲁姆 (Bupleurum chinense) 是一种中国的植物.脂质的积累 脂质的积累代谢相关的脂肪肝疾病氧化应激是一种氧化应激.赛科萨尼尼C是一种在Sirtuin 6中使用.

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