一个可穿戴系统,通过通过皮肤介质神经刺激来实现急性压力监测和闭环缓解
Farhan N Rahman1, Prabhkirat S Bindra1, Afra Nawar1
1School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, 30332, United States.
Biosensors & bioelectronics
|February 10, 2026
概括
这项研究开发了一种可穿戴设备,用于使用心血管信号和通过穿皮中枢神经刺激 (tMNS) 缓解持续的急性压力监测. 该系统准确地跟踪压力并有效地减少其影响,为潜在的临床应用铺平了道路.
科学领域:
- 生物医学工程 生物医学工程
- 心血管生理学心血管生理学
- 可穿戴技术可穿戴技术
背景情况:
- 过度的急性压力会带来心血管风险,包括疾病和心脏突然死亡.
- 通过皮肤间神经刺激 (tMNS) 显示出通过神经调节减轻急性压力的前景.
- 在急性压力事件期间,持续监测对于有针对性的tMNS传递至关重要.
研究的目的:
- 开发一种可穿戴系统,用于闭环的急性应激监测和缓解.
- 该系统与tMNS集成了非侵入性心血管传感.
- 目标是提供实时,有针对性的压力管理.
主要方法:
- 设计了一种用于手腕的设备,其中包含光电心电图 (PPG) 和加速度计传感器.
- 从PPG信号中提取脉冲率 (PR) 和PPG振幅 (PPGamp).
- tMNS是通过内置模拟电路传递的,通过伴随应用程序无线控制.
主要成果:
- 该设备的PR测量与心电图衍生的心率 (HR) 有很强的相关性 (r=0.871,p<0.001).
- 在压力期间,tMNS应用增加了PPG振幅,使其恢复到基线和超越.
- 在tMNS后的PR减少反映了PPGamp的增加,表明成功减轻了压力.
结论:
- 这是使用心血管传感和tMNS进行持续的急性压力监测和缓解的首个可穿戴系统.
- 该设备展示了跟踪压力和减少其生理影响的能力.
- 未来的研究应该专注于门诊测试和临床应用,用于诸如焦虑和创伤障碍等疾病.
相关概念视频
01:17Open and closed-loop control systems
1.8K
Control systems are foundational elements in automation and engineering. They are broadly categorized into open-loop and closed-loop systems. These classifications hinge on the presence or absence of feedback mechanisms, significantly influencing the system's performance, complexity, and application.
An open-loop control system operates without feedback from the output. It consists of two primary elements: the controller and the controlled process. The controller receives an input signal...
An open-loop control system operates without feedback from the output. It consists of two primary elements: the controller and the controlled process. The controller receives an input signal...
1.8K
01:08Median
29.4K
Besides mean, the median is a widely used measure of central tendency. Typically, median is defined as the central or middle value of a data set, measured by arranging the data elements in an increasing or decreasing order. Since this middle value is not affected by the precise numerical values of the outliers or fluctuations, it is insensitive to them. Hence, in cases where a data set may have outliers or the extreme values are not known, the median is a better measure of the central tendency...
29.4K
01:20Sign Test for Median of Single Population
372
In general, the sign test serves as a nonparametric method to test hypotheses about the median of a single population when the data does not follow a known distribution. This simplicity makes it particularly useful for small sample sizes or when the assumptions of parametric tests cannot be met. The process begins with identifying a null hypothesis, typically stating that the population median equals a specific value. The alternative hypothesis could be that the median is either not equal to,...
372
02:02Responses to Salt Stress
14.7K
Salt stress—which can be triggered by high salt concentrations in a plant’s environment—can significantly affect plant growth and crop production by influencing photosynthesis and the absorption of water and nutrients.
14.7K
01:01Feedback Loops
64.7K
In most cases, excessive hormone production is prevented by negative feedback—a loop that starts with a stimulus inducing the release of a particular substance, like a hormone, to maintain a certain level before triggering a signal that results in a decrease in further release of the hormone.
64.7K
01:29Close Relationships and Culture
250
Culture shapes how people approach attraction, choose partners, and build long-term relationships. While some preferences in mate selection appear consistent across cultures, such as men valuing physical attractiveness and women emphasizing financial resources, cultural contexts influence how these preferences are expressed and prioritized. Marriage extends beyond romantic ideals in many societies and is deeply embedded in social, economic, and religious frameworks.The Role of Culture in Mate...
250