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Updated: Feb 12, 2026

Perspectives on Neuroscience
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4β-基胆固醇作为CYP3A诱导的内源生物标志物:科学理由,临床效用和未来的前景

Barry Jones1

  • 1Global DMPK, Pharmaron UK, Pegasus Way, Crown Business Park, Rushden, Northamptonshire, NN10 6ER, United Kingdom.

Drug metabolism and pharmacokinetics
|February 10, 2026
PubMed
概括

4β-基胆固醇 (4β-HC) 是检测慢性CYP3A诱导的稳定生物标志物. 虽然对于长期监测是有用的,但其长半衰期限制了急性反应评估,需要进一步改进方法.

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