在患有双相情感障碍的年轻人中,酒精使用和酒精使用障碍的相关性
Alysha A Sultan1, Chon Hei Wong2, Benjamin I Goldstein3
1Centre for Youth Bipolar Disorder, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Journal of psychiatric research
|February 10, 2026
概括
患有双相情感障碍 (BD) 和酒精使用或酒精使用障碍 (AUD) 的年轻人表现出增加的冲动性和其他并发症. 酒精使用障碍与更严重的内部化和外部化问题有关,突出了干预的目标.
科学领域:
- 精神病学是一个精神病学.
- 青少年健康 青少年健康
- 神经科学是一个神经科学.
背景情况:
- 酒精使用和酒精使用障碍 (AUD) 在患有双相情感障碍 (BD) 的年轻人中越来越普遍.
- 对于青少年这种并发症的临床相关性,人们的了解有限.
研究的目的:
- 调查与酒精使用和AUD相关的人口和临床特征在BD的年轻人中.
- 为了确定与AUD相比,患有BD的年轻人体验酒精使用之间的并发症差异.
主要方法:
- 一组250名青少年 (13-20岁) 患有BD被分为没有酒精使用,酒精使用或终身AUD组.
- 使用多项和二进制逻辑回归分析来检查临床因素与酒精使用状态之间的关联,并根据年龄和性别进行调整.
主要成果:
- 与没有使用酒精的年轻人相比,使用酒精或AUD的年轻人表现出更高的药物使用障碍,吸烟和冲动性.
- AUD与老年,反对性挑性障碍 (ODD),行为障碍 (CD),饮食障碍,抑郁,情绪失调和人际关系问题有关.
- 与那些只饮酒的年轻人相比,患有AUD的年轻人显示出ODD和CD的比率更高.
结论:
- 青少年患有BD的酒精使用和AUD与增加的冲动性和物质使用有关.
- AUD与更多的内化和外化并发症有关,与单独使用酒精相比,观察到的不良相关性更多.
- 确定的临床相关性为预防和治疗策略提供了潜在的目标,以减轻这一群体的负面结果.
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