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Updated: Feb 12, 2026

Using 22C3 Anti-PD-L1 Antibody Concentrate on Biopsy and Cytology Samples from Non-small Cell Lung Cancer Patients
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通过Orai1和STIM1介导的信号控制PD-L1的表达,并调节口腔癌的抗瘤免疫力

Eriko Yamashita1, Soichiro Ishikawa2, Yuto Mizuno3

  • 1Cardiovascular Research Institute, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama-shi, Kanagawa 236-0004, Japan; Department of Oral and Maxillofacial Surgery, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama-shi, Kanagawa 236-0004, Japan.

The journal of physiological sciences : JPS
|February 10, 2026
PubMed
概括

这项研究表明,信号调节口腔癌中PD-L1的表达. 抑制储存运行的入 (SOCE) 降低PD-L1,可能改善抗瘤免疫力.

关键词:
干扰素玛 (IFN-γ) 是一种干扰素.口腔状细胞癌 (OSCC) 是一种在PD-L1中.储存运行的入口 (SOCE)瘤的免疫规避是瘤的免疫规避.

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