峰会计划缩短退伍军人的长期阿片类药物治疗:混合方法可行性研究
Sara N Edmond1, Danielle M Wesolowicz2, Brent A Moore2
1VA Connecticut Healthcare System, West Haven, Connecticut; Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.
The journal of pain
|February 10, 2026
概括
一项试点研究发现,支持阿片类药物逐渐减少的基于网络的应用程序显示出高患者保留率和可接受性. 然而,低招生率和应用程序使用率表明,需要为未来的试验修改招聘策略.
科学领域:
- 疼痛管理 疼痛管理
- 数字健康数字健康
- 行为治疗是一种行为疗法.
背景情况:
- 长期的阿片类药物治疗带来风险,往往没有好处,需要以患者为中心的支持性治疗.
- 在阿片类药物逐渐减少期间,临床医生和患者面临着挑战,包括资源限制和对疼痛增加的恐惧.
研究的目的:
- 评估峰会基于Web的应用程序的可行性和可接受性,以支持自愿的阿片类药物逐渐减少.
- 通过为期九个月的随机试点可行性试验,评估峰会计划进行全面试验的潜力.
主要方法:
- 一个随机的试点可行性试验 (NCT04746833) 涉及44名患者超过9个月.
- 参与者被随机分配到激励面试以及Summit应用程序或控制疼痛监测应用程序.
- 可行性 (入学,留住,使用计划) 和可接受性 (定量和质量) 是主要结果.
主要成果:
- 该研究实现了4.9%的招生率,招募了44名患者.
- 虽然峰会网站的使用率很低,但研究保留率和干预接受率在两支机构都很高.
- 大约三分之一的参与者减少了阿片类药物剂量,定性反表明疼痛感知发生了积极的转变.
结论:
- 峰会应用程序显示了高的接受度和保留率,这表明支持阿片类药物逐渐减少的潜力.
- 招聘和计划利用方面的挑战需要对未来的大规模试验的招生策略进行修改.
- 尽管应用程序的使用率很低,但试点项目为患者在减少阿片类药物剂量期间的支持提供了宝贵的见解.
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