可转移的元素有助于宿主转移相关基因的进化,这种变化发生在形类类物种中
Daniel Siqueira de Oliveira1,2,3, Anaïs Larue2, William Vilas Boas Nunes2
1São Paulo State University (Unesp), Institute of Biosciences, Humanities and Exact Sciences, São José do Rio Preto, São Paulo 15054-000, Brazil; claudia.carareto@unesp.br cristina.vieira@univ.lyon1.fr.
Genome research
|February 10, 2026
概括
可转移的元素 (TE) 驱动了状的进化分歧. 这些TEs影响宿主转移相关的基因,有助于昆虫的物种化和生殖隔离.
科学领域:
- 进化生物学 进化生物学
- 基因组学就是基因组学.
- 昆虫科学 昆虫科学 昆虫科学
背景情况:
- 昆虫宿主转移对于物种化至关重要,涉及与宿主相互作用相关的基因的基因和转录基因变化.
- 仙人掌的多种类型为研究宿主转移进化提供了有价值的模型,因为它们具有多样化的仙人掌宿主和特定物种的偏好.
- 可转移元素 (TE) 是已知的基因新性和快速适应性进化的驱动因素,但它们在昆虫宿主转移中的作用在很大程度上尚未被探索.
研究的目的:
- 调查可移植元素 (TE) 和宿主转移相关基因之间的相互作用.
- 探索TEs对与宿主转移相关的基因组和转录组分歧的贡献.
主要方法:
- 基因组和转录基因组分析对六个型Drosophila物种/亚种的基因组进行了分析.
- 分析了与宿主转移相关的基因在促进区域的TE分布和丰富.
- 在具有不同宿主偏好的物种之间进行了基因表达差异分析.
- 量化了基因-TE仿真转录的生成.
主要成果:
- 转录因子在与宿主转移相关的基因的促进子区域中富含,约39%的气味受体在转录因子内具有转录因子结合位.
- 大约50%的这些TEs是Helitrons,这表明Helitrons在Drosophila中扮演着重要的cis-regulatory角色.
- 在具有不同宿主偏好的物种之间的头和幼虫中观察到基因表达差异.
- 虽然TEs不会影响整体基因表达,但6.27%的表达基因形成基因-TE化学转录,包括影响宿主偏好的基因.
结论:
- 可转移的元素在经历宿主转移的多索菲拉物种之间推动分歧方面发挥着重要作用.
- 转基因,特别是Helitrons,可能充当影响宿主偏好关键基因的cis-regulatory元素.
- 基因-TE化学转录的形成有助于在宿主转移期间的适应性进化和生殖隔离.
相关概念视频
Genome Size and the Evolution of New Genes
9.2K
While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.
9.2K
Genome Size and the Evolution of New Genes
3.5K
3.5K
Gene Evolution - Fast or Slow?
8.2K
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
In contrast, regions which code...
8.2K
Gene Evolution - Fast or Slow?
3.7K
3.7K
The Evidence for Evolution
48.4K
Genetic variations accumulating within populations over generations give rise to biological evolution. Evolutionary changes can result in the formation of novel varieties and entire new species. These changes are responsible for the diverse forms of life inhabiting the planet. The evidence for evolution suggests that all living organisms descended from common ancestors.
48.4K
Gene Flow
38.0K
Gene flow is the transfer of genes among populations, resulting from either the dispersal of gametes or from the migration of individuals.
38.0K


