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Updated: Feb 12, 2026

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在全身性硬化症中激活PD-1通路会减轻由炎症驱动的纤维化

Maithri Aspari1, Voon Ong2, Klaus Søndergaard3

  • 1Department of Biomedicine, Aarhus University, Aarhus, Denmark.

Annals of the rheumatic diseases
|February 10, 2026
PubMed
概括

调节编程细胞死亡蛋白1 (PD-1) 途径可以减少扩散性皮肤系统性硬化症 (dcSSc) 模型中的炎症和纤维化. 这表明,针对PD-1轴为dcSSc提供了一个新的治疗策略.

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