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Updated: Feb 12, 2026

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通过对抗IL-18感应,IL-4-STAT6信号延迟了保护性CD8+T细胞旁观者激活

Nicholas J Maurice1,2, Talia S Dalzell3,4, Trevor N Tankersley3,4

  • 1Center for Immunology, University of Minnesota Medical School, Minneapolis, MN, USA. maurice@umn.edu.

Nature immunology
|February 10, 2026
PubMed
概括

介乐-4 (IL-4) 通过限制IL-18感应来对抗记忆CD8+T细胞的旁观者激活. 之前的抗原暴露取代了IL-4的影响,确保了强大的免疫反应.

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