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Updated: Feb 12, 2026

Author Spotlight: A Model to Study the Systemic and Local Dynamics of CD8+ T Cells During LN Metastasis
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Published on: January 26, 2024

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Flt3L介导的瘤cDC1扩张通过在淋巴结中的干状CD8+ T细胞进行原始化来增强免疫疗法

Junyun Lai1,2, Cheok Weng Chan1,2, Jesse D Armitage1,2,3,4

  • 1Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.

Nature immunology
|February 10, 2026
PubMed
概括

扩张的树突细胞与Fms相关的氨酸激酶3联体 (Flt3L) 增强了抗瘤免疫力. 这种组合疗法增强了T细胞对抗癌症的反应,改善了治疗结果.

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