人类指数和身体成分指数与慢性炎症疾病中亚临床动脉损伤之间的关联
Panagiota Kaloudi1,2, Athanase D Protogerou1,3, Evaggelia K Aissopou1
1Cardiovascular Prevention & Research Unit, Clinic & Laboratory of Pathophysiology, Department of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
International journal of obesity (2005)
|February 10, 2026
概括
在患有慢性炎症性疾病 (CID) 的患者中,像BMI这样的常见体质指数与动脉损伤无关. 具体措施,如体脂百分比和腰围,显示与动脉内介质厚度的关联.
科学领域:
- 心血管健康 心血管健康
- 炎症性疾病 炎症性疾病
- 动脉健康 动脉健康
背景情况:
- 亚临床动脉损伤 (SAD) 与超重/肥胖个体的人类指数有关.
- 关于慢性炎症性疾病 (CID) 患者的SAD标志物的数据有限.
研究的目的:
- 测试人类指数和SAD标志物之间的关联是否在CID患者与非CID患者之间有所不同.
- 为了研究与身体组成有关的宏观和微循环SAD标记物.
主要方法:
- 纳入了264名患有CID的患者和491名患有心血管风险因素的没有CID的患者.
- 评估了人体测量测量,动脉内膜介质厚度 (IMT),脉冲波速度 (PWV) 和视网膜血管口径.
主要成果:
- 在非CID个体中,大多数人体指数与IMT和视网膜血管口径相关.
- 在CID患者中,只有身体脂肪百分比,中上臂周长和腰围与IMT相关.
- 在CID患者中,没有人体指数与视网膜微循环有关;在任何一组中都没有PWV的关联.
结论:
- 像体重和BMI这样的标准指数与CID患者的SAD标志物无关.
- 在CID的存在下,某些人体指数的临床实用性可能受到限制.
- 需要进一步的研究来澄清CID对SAD标记器关联的影响.
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