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Updated: Feb 12, 2026

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关于更年期症状和治疗的患者偏好:对定量陈述偏好研究的系统审查
Lucie Raskin1, Emma Boretti2, Jonathan Douxfils2,3
1Research Unit in Clinical Pharmacology and Toxicology, Namur Research Institute for Life Sciences (NARILIS), Faculty of Medicine, University of Namur, Rue de Bruxelles 61, 5000, Namur, Belgium. Lucie.raskin@unamur.be.
The patient
|February 10, 2026
概括
妇女在更年期治疗中优先考虑疗效和安全性,表达对当前选择的不满. 需要进一步的研究,包括离散选择实验,以使治疗与患者偏好保持一致.
科学领域:
- 生殖医学 生殖医学
- 妇女健康 妇女健康
- 基于证据的医学基于证据的医学.
背景情况:
- 患者的期望对于更年期治疗的坚持和结果至关重要.
- 了解女性对更年期治疗的偏好是必不可少的.
- 关于女性对症状管理和治疗方式的具体偏好,数据有限.
研究的目的:
- 系统地审查关于女性对更年期症状和治疗的偏好研究.
- 为未来的研究和开发提供有效的更年期疗法的信息.
- 通过将治疗与女性期望保持一致来提高患者管理.
主要方法:
- 对Medline和Embase数据库的系统文献审查.
- 包括定量陈述偏好研究 (联合分析,离散选择实验等). 在2025年4月之前发表.
- 使用DIRECT和CROSS检查清单进行质量评估,并遵守PRISMA 2020指南.
主要成果:
- 包括七项研究 (4项联合分析,3项调查),主要来自美国和欧洲.
- 妇女优先考虑治疗疗效和长期安全性,报告对当前选择的不满.
- 对于局部雌激素疗法,人们更喜欢使用带有应用器的阴道片.
结论:
- 目前关于更年期治疗偏好的研究是有限的和异质的.
- 需要进一步的联合分析,特别是离散选择实验.
- 了解患者的偏好对于改善更年期治疗选择和患者管理至关重要.
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