在中国武汉的男性中,人类乳头瘤病毒的流行率和基因型特征:一个横截面研究
Zhiming Li1, Ruoxi Wu2, Zhiqiang Li3
1Department of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, PR China.
BMC infectious diseases
|February 10, 2026
概括
人类乳头瘤病毒 (HPV) 感染在武汉男性中很常见,低风险类型普遍存在. 年轻人和老年男性的HPV患病率最高,这凸显了有针对性的教育和疫苗接种的必要性.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 病毒学 病毒学
背景情况:
- 人类乳头瘤病毒 (HPV) 感染在全球范围内构成了重大公共卫生挑战.
- 生殖器和口腔部疾病与HPV有关,影响男性和女性.
- 关于中国武汉的男性HPV基因型特异性流行病学的数据有限.
研究的目的:
- 调查中国武汉市男性HPV的流行率和基因型分布.
- 为了解决HPV在男性人口中的综合流行病学数据的缺口.
- 为HPV预防和控制的公共卫生战略提供信息.
主要方法:
- 进行了一项回顾性横截面研究.
- 分析了来自武汉大学任民医院 (2017年1月至2025年7月) 接受HPV检测的2,999名男性的数据.
- 确定了HPV的流行率和基因型分布.
主要成果:
- 在被研究的男性中,HPV总体患病率为38.6%.
- 低风险单型感染占主导地位,其中HPV6,HPV11,HPV16,HPV52和HPV59是最常见的基因型.
- 在年轻 (≤20岁) 和年长 (≥60岁) 的年龄组中观察到HPV流行率的峰值,尽管病例比例最大的是20-39岁的年龄组.
结论:
- 在武汉的男性中,HPV感染的患病率特别高,其特点是低风险,单一类型的感染占主导地位.
- 青少年 (≤20岁) 和老年男性 (≥60岁) 是HPV感染风险最高的群体.
- 这些发现支持加强对青年和老年人的HPV教育,以及在男性中更广泛地推广HPV疫苗接种.
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