在津巴布韦青少年中,电子遵守监测的可行性,可接受性和有效性:一项混合方法研究
Nyasha V Dzavakwa1,2, Constance Rs Mackworth-Young3,4, Palwasha Y Khan5
1Biomedical Research and Training Institute, 10 Seagrave Road, Avondale, Harare, Zimbabwe. nyasha.dzavakwa@lshtm.ac.uk.
BMC global and public health
|February 10, 2026
概括
电子监测设备 (EMD) 是有效的,可行的,可接受的跟踪青少年在低收入环境中的药物坚持. 这些数字工具有望改善长期治疗的坚持.
科学领域:
- 青少年健康 青少年健康
- 数字健康数字健康
- 临床试验 临床试验
背景情况:
- 关于电子监测设备 (EMD) 评估青少年服药的有效性,可行性和可接受性的证据有限.
- 青少年面临着独特的坚持挑战,需要有效的数字工具,特别是在资源有限的环境中.
- VITALITY试验提供了一个机会,在这个人群中评估EMD.
研究的目的:
- 评估EMD的可行性,可接受性和有效性,以监测艾滋病毒感染青少年的药物坚持.
- 探索青少年对EMD的看法以及坚持不一致的原因.
- 在类似的群体和环境中,为使用数字坚持工具提供信息.
主要方法:
- 在津巴布韦VITALITY试验中进行了一项解释性顺序混合方法研究.
- 97名青少年 (年龄11-19岁) 用了EMD24周来监测维生素D补充剂的坚持.
- 通过与血清维生素D水平的相关性评估有效性;通过设备性能记录评估可行性;通过定性访谈评估可接受性.
主要成果:
- 在EMD坚持和维生素D水平之间发现了强烈的正相关性 (R2=0.42,p<0.001),支持EMD有效性.
- 尽管网络覆盖范围间歇,EMD显示出可靠的功能,没有重大故障.
- 青少年报告说,由于易于使用,谨慎和激励效益,接受度很高.
结论:
- 在低收入环境中,EMD是有效的,可行的和可接受的,用于监测青少年的遵守.
- 这些发现支持EMD的更广泛应用,以促进和监测青少年对慢性治疗的坚持.
- 在青少年群体的研究和临床实践中,可以有效地实施数字依从性监测工具.
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