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Updated: Feb 12, 2026

Whole-cell Patch-clamp Recordings for Electrophysiological Determination of Ion Selectivity in Channelrhodopsins
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Whole-cell Patch-clamp Recordings for Electrophysiological Determination of Ion Selectivity in Channelrhodopsins

Published on: May 22, 2017

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道关在后罗多普辛类道罗多普辛中,具有对比的K+和Na+选择性

Oleg A Sineshchekov1, Elena G Govorunova1, Hai Li1

  • 1Center for Membrane Biology, Department of Biochemistry & Molecular Biology, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX 77030, USA.

Biophysical journal
|February 11, 2026
PubMed
概括

两个通道罗多普辛,HcKCR1和HcCCR,使用独特的M1光循环状态进行光门离子通道开放. 这种机制在后素样阴离子通道素 (BCCRs) 中得到保护,进步了光遗传学.

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