优化面和轨道纤维发育不良症的手术管理:一个多中心回顾性研究
Lianfei Fang1, Yinwei Li1, Yining Wei1
1State Key Laboratory of Eye Health, Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Head & neck
|February 11, 2026
概括
轨道纤维发育不良症 (OFD) 患者具有独特的特征,视力丧失通常源于视神经的压缩. 复发风险因素包括多位性参与和早期手术年龄.
科学领域:
- 面外科手术 面外科手术
- 眼科医生 眼科 眼科
- 遗传学 遗传学 是一个
背景情况:
- 纤维发育不良 (FD) 是一种罕见的骨疾病,其机制尚不清楚.
- 面FD (CFD) 和轨道FD (OFD) 存在独特的临床挑战.
研究的目的:
- 评估CFD和OFD的临床特征.
- 调查OFD中视力障碍的原因.
- 确定FD中复发的风险因素.
主要方法:
- 来自三个中心的54名CFD患者的回顾性分析.
- 专注于30名带有轨道干扰 (OFD) 的患者.
主要成果:
- 更多的OFD患者患有多胞体FD和麦库恩-阿尔布赖特综合征.
- 视力障碍与视神经的压缩和拉伸有关.
- 多胞性FD独立预测复发 (p=0.034).
- 较年轻的手术年龄 (<16岁) 和异常的BMI与复发相关.
结论:
- 轨道FD具有独特的临床特征.
- 视通道减压并不总是视力丧失的必要条件.
- 在进行外科手术之前,彻底评估复发风险至关重要.
相关概念视频
Globular and Fibrous Proteins
47.2K
Many proteins can be classified into two distinct subtypes - globular or fibrous. These two types differ in their shapes and solubilities.
Globular proteins are also known as spheroproteins and typically are approximately round in shape. They contain a mix of amino acid types and contain differing sequences in their primary structures. Globular proteins have many different functions, such as enzymes, cellular messengers, and molecular transporters. These roles often require the proteins to be...
Globular proteins are also known as spheroproteins and typically are approximately round in shape. They contain a mix of amino acid types and contain differing sequences in their primary structures. Globular proteins have many different functions, such as enzymes, cellular messengers, and molecular transporters. These roles often require the proteins to be...
47.2K
Molecular Orbital Theory I
47.8K
Overview of Molecular Orbital Theory
47.8K
Atomic Orbitals
45.2K
An atomic orbital represents the three-dimensional regions in an atom where an electron has the highest probability to reside. The radial distribution function indicates the total probability of finding an electron within the thin shell at a distance r from the nucleus. The atomic orbitals have distinct shapes which are determined by l, the angular momentum quantum number. The orbitals are often drawn with a boundary surface, enclosing densest regions of the cloud.
45.2K
Urinary Tract Calculi VI: Surgical Management
560
Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
560
Inflammatory Bowel Disease V: Surgical Management
639
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
639
Molecular Orbital Theory II
27.7K
Molecular Orbital Energy Diagrams
27.7K


