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Updated: Feb 12, 2026

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
10:52

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Published on: March 30, 2018

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在耐BCR灭绝的MYC驱动B细胞淋巴瘤中有针对性的脆弱性

Silvia Brambillasca1, Nicara Chantal Parr2, Adriana Palmeri2

  • 1Experimental Therapeutics Program, IFOM ETS-The AIRC Institute of Molecular Oncology, Milano, Italy.

Hematological oncology
|February 11, 2026
PubMed
概括

波拉图祖马布维多丁在MYC驱动的淋巴瘤中面临挑战,原因是失去了B细胞受体 (BCR) 表达. 研究人员发现mTOR和CDK4/6抑制剂有效向这些BCR阴性攻击性B细胞淋巴瘤.

关键词:
B细胞受体 (BCR) 是一种B细胞受体.没有BCR的淋巴瘤在CDK4/6中使用.药物查是指对药物进行查.高度B细胞淋巴瘤高度B细胞淋巴瘤在mTOROR中使用mTOR.波拉图祖马布-维多丁是一种

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