基于性别的实践模式的低标位组O整体血液在儿科创伤的管理
Caitlin R Eason1, Lavanya Easwaran1, Julie A Rizzo2
1Department of Surgery, University of Colorado School of Medicine, Aurora, Colorado, USA.
Transfusion
|February 11, 2026
概括
儿科创伤患者在较小的儿童中表现出类似的低标位O组全血 (LTOWB) 性别使用. 然而,年长的男性青少年 (15-17岁) 比女性更有可能接受LTOWB.
科学领域:
- 儿科创伤护理 儿童创伤护理
- 大规模伤亡事件事件
- 血液输血 医学 输血 医学
背景情况:
- 创伤是美国儿童死亡和残疾的主要原因.
- 关于小儿创伤中低标位O组全血 (LTOWB) 使用的数据有限.
- 这项研究考察了儿童创伤患者LTOWB的性别差异.
研究的目的:
- 描述LTOWB在儿科创伤中的使用现行实践.
- 为了确定LTOWB管理中的潜在基于性别的差异.
- 分析LTOWB使用中的基于性别的年龄分层差异.
主要方法:
- 对创伤质量改善计划 (TQIP) 数据库 (2020-2023) 的回顾性分析.
- 包括接受任何血液制品的女性和男性儿童 (<18岁) 在使用LTOWB的中心入院后4小时内.
- 两性之间比较LTOWB的使用率,根据损伤的严重程度和机制进行调整.
主要成果:
- 16,482名儿童符合纳入标准 (4885名女性,11,597名男性).
- 男人总体上更有可能接受LTOWB (OR 1.07).
- 在年长的青少年中出现了基于性别的差异:年龄在15-17岁的男性更容易接受LTOWB (OR 1.64).
结论:
- 在年轻年龄组的男性和女性儿科患者中,LTOWB的使用类似.
- 在15-17岁的年龄组中,在LTOWB管理中出现了明显的基于性别的差异,有利于男性.
- 需要进一步的研究,以了解LTOWB利用中这些特定年龄的基于性别的差异背后的原因.
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