患有急性腹痛的患者的超胺血症:一个不寻常的病例报告
Antonia Ida Facciuto1, Carmine Nasta1, Francesca Palumbo1
1Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy.
European journal of case reports in internal medicine
|February 11, 2026
概括
肝酶升高和腹部疼痛可以表明IgG4相关疾病 (IgG4RD),这是一个罕见的疾病. 早期诊断和治疗对于预防器官损伤至关重要.
科学领域:
- 免疫学 免疫学 免疫学
- 胃肠病学 胃肠病学
- 类风湿病学 类风湿病学
背景情况:
- 超胺血症和腹部疼痛是常见的症状,有不同的原因.
- 这些非特异性发现可以掩盖严重的疾病,如IgG4相关疾病 (IgG4RD).
研究的目的:
- 呈现一种IgG4相关疾病 (IgG4RD) 病例,模仿其他腹部病理.
- 强调在肝酶升高和腹痛患者中识别IgG4RD的重要性.
主要方法:
- 一个72岁的男性患有腹痛和肝酶升高的病例报告.
- 利用成像,血清学测试 (血清IgG4水平) 和病原学进行诊断.
- 应用了2019年EULAR/ACR对IgG4RD的分类标准.
主要成果:
- 患者出现多系统参与 (胰腺,胆道,甲状腺,唾液,眼腺).
- 观察到显著升高的血清IgG4水平和IgG4阳性淋巴细胞透体.
- 该患者符合IgG4RD的分类标准.
结论:
- 非特异性症状,如高转胺血症和腹痛,可以表明罕见的系统性疾病,如IgG4RD.
- 多系统参与和高IgG4水平是关键的诊断线索.
- 及时的免疫抑制疗法对于预防IgG4RD中不可逆转的器官损伤至关重要.
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