在One Health背景下探索抗生素管理干预措施:范围审查
Léo Delpy1,2,3, Chloe Clifford Astbury4,5, Olivier Kambere Kavulikirwa6,7
1ASTRE, University of Montpellier, CIRAD, INRAE, Montpellier, France.
Frontiers in public health
|February 11, 2026
概括
抗生素耐药性 (ABR) 是一个全球性的威胁,由过度使用抗生素驱动. 一个健康的方法至关重要,但目前的干预措施往往优先考虑人类的健康,需要更好地评估跨部门的管理策略.
科学领域:
- 公共卫生 公共卫生
- 兽医医学 兽医医学 兽医医学
- 环境科学 环境科学
背景情况:
- 抗生素耐药性 (ABR) 对全球健康构成重大威胁,原因是人类,动物和食品生产部门过度使用抗生素.
- 人,动物和环境健康的相互联系需要一个健康的方法来有效地打击ABR.
- 现有的抗生素管理干预缺乏从一个健康的角度全面的概述.
研究的目的:
- 对现有的抗生素管理政策干预措施进行范围审查.
- 从一个健康的角度提供对抗生素管理干预措施的全面概述.
- 评估这些干预措施的特点,实施和影响.
主要方法:
- 在三个数据库中使用PRISMA扩展用于Scoping Reviews指导方针进行系统的文献搜索.
- 针对干预措施的有目的抽样,以根据26个变量进行详细评估.
- 提取数据的描述性分析,以总结干预特征和影响.
主要成果:
- 29个选定的干预措施重点是沟通,抗生素获取/使用和处置.
- 干预措施显示One Health方面的变化,包括跨部门合作和公平.
- 促进者包括畜牧业的参与和提供抗生素替代品;观察到对抗生素使用,耐药性,意识和动物健康的影响.
结论:
- 一个健康的抗生素管理干预往往优先考虑人类健康目标.
- 需要不断加强对这些干预措施的评估,以了解实施促进者,障碍和影响.
- 加强评估对于优化人类,动物和环境健康领域的抗生素管理策略至关重要.
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