四维自动左心房量化技术在评估心脏衰竭患者的左心房体积和功能的临床实用性与保存的射出分数
Yuehong Cheng1, Lijuan Zhang1, Lei Li2
1Department of Ultrasound, The Fourth Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Quantitative imaging in medicine and surgery
|February 11, 2026
概括
四维自动左心房量化 (4D LAQ) 有效地评估心力衰竭中左心房 (LA) 功能与保存的射出分数 (HFpEF). 左心房收缩环周应变 (LASct-c) 在这个患者群体中显示出优异的诊断性能.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 心脏衰竭研究研究
背景情况:
- 左心房 (LA) 功能障碍是心力衰竭的重要因素,具有保存的射出分数 (HFpEF).
- 对于评估HFpEF患者的LA周围菌株的研究有限.
- 四维自动左心房量化 (4D LAQ) 是评估心脏功能的一种新技术.
研究的目的:
- 调查4D LAQ技术在评估LA体积,功能和应变中的临床实用性.
- 在HFpEF中评估各种LA菌株参数的诊断性能.
- 在患有HFpEF的患者中确定LA功能障碍的关键指标.
主要方法:
- 招募了184名疑似HFpEF患者和68名健康志愿者.
- 使用H2FPEF得分将患者分为HFpEF或非HFpEF组.
- 使用4D LAQ来测量LA体积,喷射率以及各种应变参数 (纵向和周边).
主要成果:
- 与对照组相比,HFpEF患者表现出明显更高的LA体积和较低的LA射出分数.
- 在HFpEF患者中观察到LA储备和收缩应变 (纵向和周围) 的损伤.
- 左心房收缩周围应变 (LASct-c) 显示了诊断HFpEF的曲线下的最高面积 (AUC),表明了卓越的性能.
结论:
- 4D LAQ提供了一种非侵入性的,对HFpEF中的LA体积和心肌菌株的定量评估.
- LASct-c是评估HFpEF患者的LA功能的一个非常有效的参数.
- 这项技术有望改善HFpEF的诊断和管理.
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