在怀疑冠状动脉疾病的患者中,甘油三指数与冠状动脉功能之间的关系
Mengyu Chen1,2, Bing Liu1,2, Xu Li1,2
1Department of Radiology, Clinical School of Cardiovascular Disease, Tianjin Medical University, Tianjin, China.
Quantitative imaging in medicine and surgery
|February 11, 2026
概括
甘油三糖 (TyG) 指数是胰岛素耐药性的标志物,与冠状动脉血管功能较差有关. 在怀疑冠状动脉疾病 (CAD) 的患者中,较高的TyG指数值与降低的冠状动脉流量储备 (CFR) 和计算机断层扫描衍生的分量流量储备 (CT-FFR) 相相关.
科学领域:
- 心脏病学 心脏病学
- 代谢综合征是代谢综合征的一种.
- 诊断成像 诊断成像 诊断成像
背景情况:
- 胰岛素抵抗 (IR) 是冠状动脉疾病 (CAD) 的已知危险因素.
- 甘油三糖指数 (TyG) 作为IR的实际指标.
- 评估冠状动脉功能对于诊断和管理CAD至关重要,CT-FFR和CFR是关键指标.
研究的目的:
- 调查TyG指数与冠状动脉血管功能之间的关联.
- 在怀疑CAD的患者中评估TyG指数和CT-FFR和CFR之间的关系.
主要方法:
- 一项涉及293名接受SPECT和CCTA治疗的患者的研究.
- 分析CT-FFR,心肌血流量 (MBF),心肌血流量和TyG指数之间的关系.
主要成果:
- 较高的TyG指数与较低的CT-FFR,休息MBF,压力MBF和CFR有关.
- 泰格指数显示与左心室 (LV) CFR 有负相关性.
- 在没有阻塞性CAD的患者中,较高的TyG指数与降低的CFR相关,表明微循环功能障碍.
结论:
- 泰格指数独立地与冠状动脉血管功能受损有关,影响了心上膜和微循环方面.
- 在没有阻塞性CAD和降低CFR的患者中提升的TyG指数突出显示了其与微循环功能障碍和潜在的微血管损伤的联系.
- 这些发现表明,TyG指数可以为怀疑CAD的临床风险评估提供有价值的见解.
关键词:
三甘油-葡萄糖指数 (TyG指数)冠状动脉疾病 (CAD) 是一种冠状动脉疾病.冠状动脉流量储备 (CFR) 是指分流储备 (FFR) 是指分流储备.心肌动脉血流 (MBF) 是指心肌动脉的血液流动.更多相关视频
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