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Updated: Feb 12, 2026

Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro
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一种水友互动的UPLC-MS/MS定量方法,用于在人肝微粒基因组中量化萨拉卡提尼布,并在in vitro代谢稳定性评估中的应用

Mohamed W Attwa1, Adnan A Kadi1

  • 1Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. mzeidan@ksu.edu.sa.

Analytical methods : advancing methods and applications
|February 11, 2026
PubMed
概括

这项研究开发了一种快速的UPLC-MS/MS方法,用于在肝脏显微体中测量沙拉基提尼布 (SRB),揭示其代谢稳定性. 在形分析表明,结构修改可以改善SRB.

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