妊娠前血压与体外受精的生殖结果之间的关联
Yuan Fang1,2,3,4,5,6,7, Ze Wang1,2,3,4,5,6,7, Yan Li1,2,3,4,5,6,7
1State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health (Y.F., Z.W., Y. Li, X.S., L.Z., Y.N., J.Z., D.Z., G.O., H.X., N.L., Y. Liu, C.L., Y.W., Y.Q., D.W., Z.-J.C.), Shandong University, China.
新的高血压指南可能会影响体外受精的成功. 患有第一或第二阶段高血压的女性在试管婴儿期间活产率较低,妊娠并发症风险增加. 这凸显了血压管理对于生育治疗的重要性.
科学领域:
- 生殖医学 生殖医学
- 心血管健康 心血管健康
- 产科 产科 产科 产科 产科
背景情况:
- 更新的高血压指南 (2025,2017年ACC/AHA) 将诊断值降至130/80毫米.
- 这种新的高血压分类对生殖结果的影响仍然不清楚.
研究的目的:
- 调查孕前血压 (BP) 水平与接受体外受精 (IVF) 的女性生殖结果之间的关联.
主要方法:
- 在中国的生殖医学中心进行的回顾性队列研究.
- 根据IVF前的血压测量,将43,629名女性分为正常血压,高血压,第一阶段高血压和第二阶段高血压组.
- 检查了BP类别和IVF周期结果之间的关联.
主要成果:
- 与正常血压 (49.2%) 相比,患有第一阶段和第二阶段高血压的妇女的活产率明显较低 (46.1%和41.4%).
- 第1阶段和第2阶段的高血压与妊娠丧失,孕前和早产的风险增加有关.
- 高血压与更高的妊娠高血压风险有关;最佳的血压切断与第一阶段的高血压诊断保持一致.
结论:
- 妊娠前1期和2期高血压与IVF后的活产率降低有关.
- 这些高血压阶段也增加了不良妊娠并发症的风险,包括流产和子宫前.
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