巴西被忽视的真菌菌:25年来基于人口的死亡率和住院死亡率的研究
Anderson Fuentes Ferreira1, Jorg Heukelbach1, Eliana Amorim de Souza2
1Programa de Pós-Graduação Em Saúde Pública, Faculdade de Medicina, Universidade Federal Do Ceará, Fortaleza, Ceará, Brazil.
Mycoses
|February 11, 2026
概括
系统性真菌病导致巴西0.07%的死亡,男性和老年人死亡率更高. 虽然总体死亡人数下降,但住院死亡人数没有显著的趋势,这突显了改善真菌病策略的必要性.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 菌类学 菌类学是指菌类学.
背景情况:
- 系统性真菌菌是一种重要的,但往往被忽视的公共卫生问题.
- 了解它们的流行病学模式对于有效干预至关重要.
研究的目的:
- 从2000年到2024年,分析巴西因系统性真菌病而导致的死亡率和住院死亡率的流行病学,贡献因素,空间分布和时间趋势.
- 通过使用国家数据,提供有关真菌病负担的全面概述.
主要方法:
- 全国范围的生态研究利用死亡证明和住院数据.
- 采用时间和空间分析来评估死亡率,趋势 (年均百分比变化) 和地理差异.
- 对社会人口统计因素的计算率比率 (RR) 和95%置信区间 (CI).
主要成果:
- 系统性真菌病占所有死亡病例的0.07% (22230例),总死亡率为每10万人口中的0.46.
- 在男性和60-69岁的人群中,死亡率更高. 全国范围内的死亡率呈现下降趋势 (AAPC -1.12%).
- 住院死亡 (4,471例) 在男性和70岁以上的人群中更为常见,但没有观察到全国性的显著趋势. 在巴西各州发现了显著的空间异质性.
结论:
- 这项研究提供了一个独特的全国性的分析,从系统性真菌病的长期和住院死亡率.
- 忽视的真菌感染仍然是巴西死亡的关键原因,需要加强监测和控制措施.
- 独特的流行病学模式强调了巴西医疗保健系统内加强预防,控制和治疗策略的必要性.
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