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评估晚期癌症的整体生存益处:外部比较对象队列研究与现实世界数据的作用

Francesco Pignatti1, Tarec Christoffer El-Galaly2, Martin Kaiser3

  • 1The European Medicines Agency, Amsterdam, The Netherlands.

Clinical pharmacology and therapeutics
|February 11, 2026
PubMed
概括

使用真实世界数据 (RWD) 的外部比较者队列 (ECC) 研究被认为是癌症治疗单臂试验 (SAT) 的更强有力的证据. 更高质量的RWD ECC研究显示出更大的整体生存 (OS) 益处,获得了更高的证据强度评级.

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