在患有昏迷的患者中,PR间隔和复发性昏迷和全因死亡的风险
Asger Knudsen1, Johannes Jan Struijk1, Sam Riahi2,3
1Department of Health Science and Technology Aalborg University Aalborg Denmark.
Journal of the American Heart Association
|February 11, 2026
概括
在昏迷患者中,短PR间隔增加了全因死亡风险. 长时间的PR间隔与更高的复发性昏迷率有关. 这项研究强调了PR间隔在风险评估中的意义.
科学领域:
- 心脏病学 心脏病学
- 临床电生理学 临床电生理学
- 公共卫生 公共卫生
背景情况:
- 综合症风险评估经常忽视PR间隔的持续时间.
- 短PR间隔与心房动和死亡率有关.
- 了解PR间隔在昏睡结果中的作用至关重要.
研究的目的:
- 调查PR间隔持续时间与昏迷患者全因死亡率之间的关联.
- 为了探索PR间隔持续时间和复发性昏迷之间的关系.
主要方法:
- 在住院24小时内,分析了52 038名昏迷患者的心电图.
- 患者分为短 (<120毫秒),正常 (120-200毫秒) 或长 (>200毫秒) 的PR间隔组.
- 排除患有心电图异常或影响PR间隔或结果的并发症的患者.
主要成果:
- 短PR间隔与所有原因死亡率的1.50危险比率相关 (P<0.001).
- 长PR间隔与所有原因死亡率没有关联 (HR1.02,P=0.3566).
- 长PR间隔与复发性的1.14危险比相关 (P<0.001).
结论:
- 短PR间隔是昏迷患者全因死亡率增加的重要预测因素.
- 长时间的PR间隔与更高的复发性昏迷发病率有关.
- 在风风险分层中,应考虑PR间隔的持续时间.
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