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Updated: Feb 12, 2026

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Preparation of High-Quality Fermented Fish Product
Published on: August 23, 2019
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在Massa Medicata Fermentata的化合物的发酵驱动的变化
Wei Zheng1, Jiaqi Li1, Lei Yin2
1School of Pharmacy, Liaoning University of Traditional Chinese Medicine, Liaoning, China.
Biomedical chromatography : BMC
|February 11, 2026
概括
发酵显著改变了Massa Medicata Fermentata (MMF) 中的化合物,增强了其抗氧化和抗炎作用. 本研究确定了货币货币基金质量控制的关键基标志物.
科学领域:
- 药理学 药理学是指药理学的学科.
- 自然产品化学 自然产品化学
- 代谢学 代谢学 代谢学
背景情况:
- 酸药 (Massa Medicata Fermentata,简称MMF) 是一种传统的中医药,用于治疗胃肠道和代谢障碍.
- 由于缺乏可靠的参考材料,货币市场基金的质量控制具有挑战性.
- 类化合物对于MMF的治疗效果至关重要.
研究的目的:
- 调查发酵对金钱市场鱼的性特征的影响.
- 了解发酵如何增强MMF的生物活性.
- 为了识别MMF质量标准化潜在的基标记物.
主要方法:
- 使用基于超高性能液体染色学-电喷射电离-质谱学 (UPLC-ESI-MS/MS) 的代谢学.
- 在发酵 (MMF) 和未发酵 (BMMF) 的MMF中鉴定和量化了化合物.
- 评估了抗氧化剂和抗炎活性,并与类样本相关联.
主要成果:
- 确定了119种化合物 (PC),其中66种是MMF新发现的.
- 发酵显著改变了的组成,增加了自由酸,甲氧化黄和黄C-糖化物.
- 与BMMF相比,MMF表现出明显增强的抗氧化和抗炎活性 (p < 0.01).
结论:
- 发酵在很大程度上重塑了MMF的性特征,有助于提高其生物活性.
- 特定的化合物与改善的抗氧化和抗炎作用有很强的相关性.
- 已识别的化合物作为确保货币市场基金的质量和有效性的潜在标记物.
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