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Updated: Feb 12, 2026

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通过CysLT1受体对抗剂激活TMEM175 lysosomal离子通道

Kangjun Li1, Vaishali Satpute Janve2, Samantha D Le1

  • 1Department of Pharmacology, Vanderbilt University, Nashville, TN 37232.

American journal of physiology. Cell physiology
|February 11, 2026
PubMed
概括

这项研究确定了TMEM175 (跨膜蛋白175) 的新激活剂,这是一种与帕金森病相关的通道. 发现Zafirlukast是一种中等强度的TMEM175激活剂,提供潜在的治疗途径.

关键词:
激进主义者的激进主义者离子通道 离子通道lysosome 是一种溶解体.药理学 药理学是指药理学的学科.

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