节律控制在心房功能性心回中的价值 在左心室喷射分数保存的患者中
A F Safarova1, Zh D Kobalava1, S B Adam1
1Patrice Lumumba Peoples' Friendship University of Russia (RUDN University), Moscow.
Kardiologiia
|February 11, 2026
概括
功能性心房部反 (FAMR) 在心房 (AF) 患者中更严重,并预测心力衰竭与保留射出分数 (HFpEF) 的更糟糕结果. 节律控制可以改善预后.
科学领域:
- 心脏病学 心脏病学
- 心脏电生理学 心脏电生理学
- 心脏衰竭研究研究
背景情况:
- 保持喷射分数 (HFpEF) 的心力衰竭是一个重大的临床挑战.
- 功能性心房 mitrale 反 (FAMR) 是 HFpEF 的一个常见并发症.
- FAMR对结果的影响,特别是与心房动 (AF) 相关的影响,需要进一步阐明.
研究的目的:
- 为了确定HFpEF患者FAMR的发病率,严重程度和预测因素.
- 评估FAMR对临床结果的影响,基于AF的存在或不存在.
- 评估FAMR与诸如心力衰竭 (HF) 再住院,心血管死亡 (CVD) 和复合终点 (CE) 等结果之间的关联.
主要方法:
- 从2020年至2023年期间住院的218名HFpEF患者的FAMR数据的回顾性分析.
- 平均随访时间为589天.
- 在AF患者和鼻节律 (SR) 患者之间的结果比较.
主要成果:
- 与SR患者相比,AF患者中中度和重度FAMR的患病率明显高于SR患者 (53.3%对24.5%和15.3%对8.0%;p<0.001).
- 在AF小组中,严重的FAMR独立预测HF再住院风险增加 (OR4.1,p=0.002) 和CE (OR2.6,p=0.002).
- 在SR患者中没有观察到FAMR和临床结果之间的显著关联.
结论:
- 在AF的背景下,功能性心房腹是HFpEF预后不佳的独立预测因子.
- 这些发现强调了节律控制策略对于管理AF和FAMR的HFpEF患者的重要性.
- 向节律控制可能是这个脆弱的患者群体的关键病原学方法.
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