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Updated: Feb 13, 2026

De Novo Generation of Somatic Stem Cells by YAP/TAZ
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核PD-L1通过固体瘤中的PGE-EP4-YAP-importin α3轴调节YAP驱动的转录

Shakti Ranjan Satapathy1, Anita Sjölander1

  • 1Cell and Experimental Pathology, Department of Translational Medicine, Lund University, Malmö, Sweden.

Cell reports
|February 11, 2026
PubMed
概括

前列腺素E2 (PGE2) 通过通过YAP-importin-α3通路将编程死亡连接体1 (PD-L1) 移动到核中来促进癌症. 针对这个轴可能会提供一种新的癌症治疗策略.

关键词:
CP:癌症的癌症.在PD-L1中.哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈乳腺癌 乳腺癌 乳腺癌结肠直肠癌是什么意思的前列腺素E(2)

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