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Updated: Feb 13, 2026

Establishment of the Dual Humanized TK-NOG Mouse Model for HIV-associated Liver Pathogenesis
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Establishment of the Dual Humanized TK-NOG Mouse Model for HIV-associated Liver Pathogenesis

Published on: September 11, 2019

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一个人性化的IFN-γ小鼠模型揭示了皮肤伤的形成,增强的易感性和擦伤风的病原性

Ryan H Cho1, Lihai Gao1, Hui Wang2

  • 1Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America.

PLoS pathogens
|February 11, 2026
PubMed
概括

一种新的人性化小鼠模型 (hIFNG/hIFNGR) 显示对草伤寒感染的易感性增加. 这个模型模仿人类疾病,帮助研究Orientia tsutsugamushi (Ot) 和疫苗开发.

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