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深海鱼揭示了脊椎动物视觉的另一种发育轨迹
Lily G Fogg1,2, Stamatina Isari3,4, Jonathan E Barnes5
1Queensland Brain Institute, The University of Queensland, Brisbane, Queensland 4072, Australia.
Science advances
|February 11, 2026
概括
深海鱼幼虫拥有独特的混合光受体,将杆状形状与状基因结合起来. 这种适应优化了昏暗环境中的视力,挑战了传统的脊椎动物视力发展.
科学领域:
- 进化生物学是进化的生物学.
- 发育生物学是发展生物学.
- 视觉科学 视觉科学 视觉科学
背景情况:
- 脊椎动物的视力通常包括用于明亮光的形和用于模糊光的棒.
- 既定的观点是,视网膜首先形成形,其次是杆形.
- 深海鱼幼虫居住在与大多数海洋幼虫相比具有独特光线条件的环境中.
研究的目的:
- 为了研究深海鱼幼虫的光受体发育.
- 了解在暗光环境下视觉的分子和形态基础.
- 探索脊椎动物视觉中的其他发展途径.
主要方法:
- 对深海鱼幼虫光受体基因表达的比较分析.
- 对光受体细胞的形态检查.
- 通过基因和转录因子表达的发育轨迹分析.
- 频谱灵敏度预测和环境光估计.
主要成果:
- 幼虫深海鱼在杆状细胞中表现出"混合"光受体,具有型特异性基因.
- 一些物种保留了这些杂交细胞,而另一些物种则转变为真正的棒.
- 这些光受体适应暗淡,深海的光线条件,最大限度地提高视觉性能.
- 在整个开发过程中,光谱调整与普遍的光环境保持一致.
结论:
- 混合光受体代表了脊椎动物视力发展的替代策略.
- 这一发现挑战了脊椎动物状前视网膜发育的教条.
- 深海鱼提供了一个独特的模型,用于研究在极端环境压力下视觉系统的演变.
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