在有色表面水中,快速太阳光激活流感病毒和Phi6
Claire E Anderson1, Mengyang Zhang1, Gang Zheng1
1Department of Civil and Environmental Engineering, Stanford University, Stanford, California 94305, United States.
Environmental science & technology
|February 11, 2026
概括
阳光会使水中的甲型流感病毒 (IAV) 等包裹病毒失活,尤其是在有色水中. 这种光失活对于理解病毒传播和制定公共卫生战略至关重要.
科学领域:
- 环境病毒学 环境病毒学
- 摄影化学的使用.
- 公共卫生 公共卫生
背景情况:
- 间接的水中传播是流感和其他罩病毒在物种之间传播的关键.
- 太阳光在使水中的包裹病毒无活化的作用尚不清楚.
- 包裹病毒通过环境传播途径对公共卫生构成重大风险.
研究的目的:
- 在地表水中研究包裹 (Phi6,流感A病毒 - IAV) 和非包裹 (MS2) 病毒的光失活率.
- 为了确定水类型 (透明或有色) 和紫外线辐射对病毒无活化的影响.
- 阐明在水生环境中驱动阳光介导的病毒失活的机制.
主要方法:
- 模拟的阳光暴露实验在清和彩色的表面水中对Phi6,IAV和MS2进行.
- 病毒感染性试验被用来测量光选校正的衰变速率常数 (
- 用Phi6进行的额外实验探索了基激素和自然有机物质 (NOM) 的作用.
主要成果:
- 与MS2相比,IAV和Phi6的光失活率 (
- 无活化在有色水中明显快于在清水中,特别是对于IAV.
- 在有色水中,无活化率在很大程度上独立于紫外线辐射,这表明间接的光化学途径占主导地位.
结论:
- 包裹病毒,包括A型流感病毒,在水生环境中易受阳光灭活.
- 彩色溶解的有机物增强病毒的光无活化,可能是通过间接的光化学机制,涉及诸如基等反应性中间体.
- 这些发现对于评估与水传播病毒传播相关的风险和为公共卫生干预提供信息至关重要.
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