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Updated: Feb 13, 2026

Detection of Protease Activity by Fluorescent Peptide Zymography
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新型血清衍生酸作为强大的MMP-13抑制剂

Andreas Mores1, Moaz M Abdou2, Yuxin Xie3

  • 1Department of Chemistry, Laboratory of Organic Chemistry, University of Athens, Panepistimiopolis, Zografou, 15771 Athens, Greece.

Bioorganic chemistry
|February 11, 2026
PubMed
概括

研究人员开发了针对矩阵金属蛋白酶-13 (MMP-13) 的新型胺抑制剂. 化合物10a显示出强大的MMP-13抑制,尽管需要进一步优化药物相似性.

关键词:
在 ADME 预测预测.半氨酸的类似物脱水氨酸是什么 脱水氨酸是什么MMP-13 抑制剂的使用分子对接是分子对接.分子动力学分子动力学的酸是一种酸.血清类类似物 血清类类似物

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