大人的肠道微生物群,睡眠质量和认知功能:系统性审查
Hesam A Varpaei1, Lorraine B Robbins1, Mathew J Reeves2
1College of Nursing, Michigan State University, East Lansing, MI, USA.
Sleep medicine
|February 11, 2026
概括
成人的最佳睡眠和认知功能与更大的肠道微生物多样性有关. 较高的微生物多样性与更好的睡眠质量和认知表现相关,由大脑连接介导.
科学领域:
- 神经科学是一个神经科学.
- 微生物学 微生物学
- 睡眠科学 睡眠科学
背景情况:
- 肠道微生物群和睡眠质量对认知功能至关重要.
- 缺乏对肠道微生物群和睡眠对成人的认知功能的综合影响的系统审查.
研究的目的:
- 检查睡眠质量 (效率,总睡眠时间) 和肠道微生物群组成与成年人的认知功能之间的关联.
主要方法:
- 按照系统审查和元分析指南的首选报告项目进行系统审查.
- 搜索了五个在线数据库,寻找评估认知功能,睡眠质量和肠道微生物群的原始研究.
- 包括21项研究 (2901名患者),主要是横截面.
主要成果:
- 客观的睡眠测量与更大的肠道微生物多样性相关,通过大脑连接积极影响认知功能.
- 慢性失眠与肠道微生物群失调有关.
- 益生菌补充剂改善了认知障碍患者的睡眠质量和认知功能.
结论:
- 睡眠质量,肠道微生物群和成年人的认知功能之间存在复杂的相互关系.
- 最佳的睡眠和认知与更高的肠道微生物多样性有关.
- 在了解患有心血管疾病的个体中这种三位一体方面存在重大研究差距.
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